Sweet Home Alabama (2002)

directed by Andy Tennant
featuring Reese Witherspoon, Josh Lucas, Patrick Dempsey, Candice Bergen, Mary Kay Place

Can't Buy Me Love (1987)

directed by Steve Rash
featuring Patrick Dempsey, Amanda Peterson, Courtney Gains, Seth Green, Tina Caspary

Freedom Writers (2007)

directed by Richard LaGravenese
featuring Hilary Swank, Scott Glenn, Imelda Staunton, Patrick Dempsey, Mario, April Lee Hernandez

Enchanted (2007)

directed by Kevin Lima
featuring Amy Adams, Patrick Dempsey, James Marsden, Timothy Spall, Idina Menzel

Grey's Anatomy: Season 01 (2005)

Transformers: Dark of the Moon (2011)

directed by Michael Bay
featuring Shia LaBeouf, Rosie Huntington-Whiteley, Josh Duhamel, John Turturro, Tyrese Gibson, Patrick Dempsey, Frances McDormand, John Malkovich

Made of Honor (2008)

directed by Paul Weiland
featuring Patrick Dempsey, Michelle Monaghan, Kevin McKidd, Kathleen Quinlan, Sydney Pollack

Loverboy (1989)

directed by Joan Micklin Silver
featuring Patrick Dempsey, Kate Jackson, Robert Ginty, Nancy Valen, Barbara Carrera, Kirstie Alley, Carrie Fisher

Grey's Anatomy: Season 10 (2013)

Grey's Anatomy: Season 04 (2007)

Grey's Anatomy: Season 02 (2005)

With Honors (1994)

directed by Alek Keshishian
featuring Joe Pesci, Brendan Fraser, Moira Kelly, Patrick Dempsey, Josh Hamilton

Bridget Jones's Baby (2016)

directed by Sharon Maguire
featuring Renée Zellweger, Colin Firth, Patrick Dempsey, Jim Broadbent, Gemma Jones

Grey's Anatomy: Season 03 (2006)

Mobsters (1991)

directed by Michael Karbelnikoff
featuring Christian Slater, Patrick Dempsey, Richard Grieco, Costas Mandylor, F. Murray Abraham

Scream 3 (2000)

directed by Wes Craven
featuring David Arquette, Neve Campbell, Courteney Cox, Patrick Dempsey, Scott Foley

Brother Bear 2: The Moose Are on the Loose (2006)

directed by Benjamin Gluck
featuring Patrick Dempsey, Mandy Moore, Wanda Sykes, Jeremy Suarez, Rick Moranis

Grey's Anatomy: Season 09 (2012)

Coupe De Ville (1990)

directed by Joe Roth
featuring Patrick Dempsey, Arye Gross, Daniel Stern, Annabeth Gish, Rita Taggart

Jeremiah (2000)

directed by Harry Winer
featuring Patrick Dempsey, Klaus Maria Brandauer, Oliver Reed, Leonor Varela, Michael Cronin

Blonde (2001)

directed by Joyce Chopra
featuring Poppy Montgomery, Patricia Richardson, Patrick Dempsey, Wallace Shawn, Griffin Dunne

Flypaper (2011)

directed by Rob Minkoff
featuring Patrick Dempsey, Ashley Judd, Tim Blake Nelson, Mekhi Phifer, Pruitt Taylor Vince

A Season in Purgatory (1996)

directed by David Greene
featuring Patrick Dempsey, Blair Brown, Brian Dennehy, Sherilyn Fenn, Craig Sheffer, David Marshall Grant

JFK: Reckless Youth (1993)

directed by Harry Winer
featuring Patrick Dempsey, Terry Kinney, Loren Dean, Yolanda Jilot, Diana Scarwid

Lucky 7 (2003)

directed by Harry Winer
featuring Kimberly Williams-Paisley, Brad Rowe, Patrick Dempsey