Cyclic DNA adducts are formed by known human carcinogens such as vinyl chloride and benzene and a variety of rodent carcinogens including urethane and halogenated hydrocarbons. Recent evidence suggests that some of adducts are present in tissues from unexposed human subjects and could be elevated due to oxidative stress and lipid peroxidation induced by different factors (inflammation, dietary fatty acids and metal storage disorders). Some of the cyclic DNA adducts are shown to be promutagenic n bacterial and mammalian ...
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Cyclic DNA adducts are formed by known human carcinogens such as vinyl chloride and benzene and a variety of rodent carcinogens including urethane and halogenated hydrocarbons. Recent evidence suggests that some of adducts are present in tissues from unexposed human subjects and could be elevated due to oxidative stress and lipid peroxidation induced by different factors (inflammation, dietary fatty acids and metal storage disorders). Some of the cyclic DNA adducts are shown to be promutagenic n bacterial and mammalian cells. This publication brings together the latest developments in chemistry, biochemistry and repair of cyclic DNA adducts, and evaluates the role of these adducts in mutagenesis and carcinogenesis with special reference to the endogenous processes leading to initiation and/or progression of human cancers.
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Add this copy of Exocyclic Dna Adducts in Mutagenesis and Carcinogenesis to cart. $33.82, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 1999 by World Health Organization.
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Lyon 1999 1st International Agency for Research on Cancer. ISBN 9283221508. IARC Scientific Publications No. 150. Sm.4to., 361pp., printed hardcover. Sale stamp on front free blank. Publisher bound without front blank end paper o/w Fine. No ownership marks-Unused.