Fragment based ligand design is a promising technique for identifying novel lead compounds for drug discovery. Fragment based discovery involves identifying small low molecular weight compounds with low affinity to the target to use as the foundation for growing and linking to create high affinity lead compounds with high selectivity. Fragment based discovery has facilitated the incorporation of greater chemical diversity in libraries for more efficient novel lead identification This book discusses computational methods ...
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Fragment based ligand design is a promising technique for identifying novel lead compounds for drug discovery. Fragment based discovery involves identifying small low molecular weight compounds with low affinity to the target to use as the foundation for growing and linking to create high affinity lead compounds with high selectivity. Fragment based discovery has facilitated the incorporation of greater chemical diversity in libraries for more efficient novel lead identification This book discusses computational methods for fragment library design, computational docking ranking and screening of fragments and computational methods for linking and growing fragments to yield lead compounds.
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Add this copy of Library Design, Search Methods, and Applications of to cart. $88.46, fair condition, Sold by Cambridge Rare Books rated 4.0 out of 5 stars, ships from Cambridge, Gloucestershire, UNITED KINGDOM, published 2011 by OUP USA.
Add this copy of Library Design, Search Methods, and Applications of to cart. $180.64, new condition, Sold by discount_scientific_books rated 5.0 out of 5 stars, ships from Sterling Heights, MI, UNITED STATES, published 2012 by American Chemical Society.
