Sylvie Ricard-Blum

Sylvie Ricard-Blum is Professor of Biochemistry at the University of Lyon (France). She studies the structure, interactions and functions of the extracellular matrix (ECM) using biochemistry, biophysics, bioinformatics and systems biology. Her laboratory has developed a roadmap and tools to build and contextualize ECM interaction networks, including the database MatrixDB. She has identified several hundreds of ECM interactions, and built interaction networks of ECM proteins, bioactive ECM...See more

Sylvie Ricard-Blum is Professor of Biochemistry at the University of Lyon (France). She studies the structure, interactions and functions of the extracellular matrix (ECM) using biochemistry, biophysics, bioinformatics and systems biology. Her laboratory has developed a roadmap and tools to build and contextualize ECM interaction networks, including the database MatrixDB. She has identified several hundreds of ECM interactions, and built interaction networks of ECM proteins, bioactive ECM fragments (matricryptins), glycosaminoglycans and proteoglycans leading to the prediction of new functions for a number of them. Her current research aims at determining the role of intrinsic disorder, cross-linking, proteolysis and mutations in rewiring ECM networks in disease with a focus on matricryptins, lysyl oxidases and syndecans. She has been Secretary and President of the French Society for Matrix Biology, and serves as Associate Editor of Matrix Biology and Matrix Biology Plus, Editor of the newsletter of the International Society for Matrix Biology, and as President of the International Society for Matrix Biology (2019-2020). See less