This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1914 Excerpt: ... into striated muscle-cells or fibers of the skeletal type, but they never get beyond the embryonic stage of development with the nuclei centrally located between the contractile fibrils. In the slowly-growing tumors fully developed muscle-fibers of the embryonic type are formed, but in the rapidly-growing ones the ...
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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1914 Excerpt: ... into striated muscle-cells or fibers of the skeletal type, but they never get beyond the embryonic stage of development with the nuclei centrally located between the contractile fibrils. In the slowly-growing tumors fully developed muscle-fibers of the embryonic type are formed, but in the rapidly-growing ones the cells are spindle-shaped and each contains a single nucleus. Often only a few of the cells are sufficiently differentiated to produce the contractile fibrils which alone render the true character of the tumor recognizable. Gross Characteristics.--This type of rhabdomyoblastoma is rarely found outside of the genito-urinary tract (kidney, testicle, uterus, urinary bladder, prostate) although it has been reported as occurring in the orbit, the wall of the esophagus, and elsewhere in the skeletal muscles. It may grow slowly and be benign, but more commonly it grows rapidly, infiltrates, and gives rise to metastases. In gross appearances it resembles a fibrosarcoma. Striated cells and fibrils of skeletal muscle type of tumor origin are found not only in rhabdomyoblastomas, but even more often, perhaps, in the mixed tumors which occur in the genitourinary tract. 13. GLIOBLASTOMA (GLIOMA) Definition.--A tumor of epiblastic origin of which the cells tend to differentiate into neuroglia cells. Type Cell.--The type cell is the neuroglia cell. It is characterized by the production of only one kind of fibril, the neuroglia fibril, which can be stained sharply and characteristically by special staining methods. c d Fig. 264.--Glioma. Four views from different parts of the same tumor. The normal neuroglia cells are derived originally from the ependymal cells lining the neural canal and are, therefore, epiblastic in origin. The exact relation between the ependy...
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