Successful drug use in biology and medicine is often prejudiced by the failure of drugs that are otherwise active in vitro to act as efficiently in vivo. This is because in the living animal drugs must, as a rule, bypass or traverse organs, membranes, cells and molecules that stand between the site of administration and the site of action. In practice, however, drugs can be toxic to normal tissues, have limited or no access to the target and be prematurely excreted or inactivated. There is now growing optimism that such ...
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Successful drug use in biology and medicine is often prejudiced by the failure of drugs that are otherwise active in vitro to act as efficiently in vivo. This is because in the living animal drugs must, as a rule, bypass or traverse organs, membranes, cells and molecules that stand between the site of administration and the site of action. In practice, however, drugs can be toxic to normal tissues, have limited or no access to the target and be prematurely excreted or inactivated. There is now growing optimism that such problems may be resolved by the use of carrier systems that will not only protect the non-target environment from the drugs they carry but also deliver them to where they are needed or facilitate their release there. Carrier systems presently under investigation include antibodies, glycoproteins, cells, reconstituted viruses and liposomes. Recent advances in the chemistry of cell receptor and receptor-recognising molecules, llnmunology, and natural and artificial membranes have revealed a multitude of ways in which such carrier systems can be modified or improved upon.
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Add this copy of Targeting of Drugs: (Closed)) (Nato Science Series a: ) to cart. $80.89, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 2012 by Springer.
Add this copy of Targeting of Drugs to cart. $48.36, good condition, Sold by Anybook rated 4.0 out of 5 stars, ships from Lincoln, UNITED KINGDOM, published 1982 by Plenum Press.
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Seller's Description:
This is an ex-library book and may have the usual library/used-book markings inside. This book has hardback covers. Clean from markings. In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item, 1000grams, ISBN: 030641001X.
Add this copy of Targeting of Drugs (Nato Science Series a: ) to cart. $56.64, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 1982 by Plenum Press.
