A panel of leading academic and pharmaceutical investigators takes stock of the remarkable work that has been accomplished to date with proteasome inhibitors in cancer, and examines emerging therapeutic possibilities. The topics range from a discussion of the chemistry and cell biology of the proteasome and the rationale for proteasome inhibitors in cancer to a review of current clinical trials underway. The discussion of rationales for testing proteasome inhibitors in cancer models covers the role of the proteasome in NF ...
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A panel of leading academic and pharmaceutical investigators takes stock of the remarkable work that has been accomplished to date with proteasome inhibitors in cancer, and examines emerging therapeutic possibilities. The topics range from a discussion of the chemistry and cell biology of the proteasome and the rationale for proteasome inhibitors in cancer to a review of current clinical trials underway. The discussion of rationales for testing proteasome inhibitors in cancer models covers the role of the proteasome in NF-kB activation, the combining of conventional chemotherapy and radiation with proteasome inhibition, notably PS-341, new proteasome methods of inhibiting viral maturation, and the role of protesome inhibition in the treatment of AIDS. The authors also document the development of bortezomib (VelcadeTM) in Phase I clinical trials and in a multicentered Phase II clinical trials in patients with relapsed and refractory myeloma.
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Add this copy of Proteasome Inhibitors in Cancer Therapy to cart. $44.22, very good condition, Sold by UHR Books rated 5.0 out of 5 stars, ships from Hollis Center, ME, UNITED STATES, published 2004 by Humana Press.
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Very Good + Book Discusses the proteasome inhibitors use in cancer therapy, including cancer drug development, chemistry and cell biology of the proteasome, the rationale for proteasome inhibitors in cancer, and clinical trials. Illustrated. From the Cancer Drug Discovery and Development series.
Add this copy of Proteasome Inhibitors in Cancer Therapy to cart. $47.50, new condition, Sold by discount_scientific_books rated 5.0 out of 5 stars, ships from Sterling Heights, MI, UNITED STATES, published 2004 by Humana.
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Add this copy of Proteasome Inhibitors in Cancer Therapy to cart. $159.69, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2004 by Humana.