As a starting point to this volume, the authors address the fundamental question What underlying forces are responsible for the observed patterns of variability, given a collection of DNA sequences? In approaching this question they introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model and the infinite sites model. They then discuss the complications that come from nonconstant population size, recombination, population subdivision and three forms of natural ...
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As a starting point to this volume, the authors address the fundamental question What underlying forces are responsible for the observed patterns of variability, given a collection of DNA sequences? In approaching this question they introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model and the infinite sites model. They then discuss the complications that come from nonconstant population size, recombination, population subdivision and three forms of natural selection: directional selection, balancing selection and background selection. These theoretical results set the stage for the investigation of various statistical tests to detect departures from neutral evolution.
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Add this copy of Probability Models for Dna Sequence Evolution to cart. $36.67, good condition, Sold by Phatpocket Limited rated 4.0 out of 5 stars, ships from Waltham Abbey, ESSEX, UNITED KINGDOM, published 2002 by Springer.
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Add this copy of Probability Models for Dna Sequence Evolution to cart. $39.38, very good condition, Sold by Cambridge Rare Books rated 4.0 out of 5 stars, ships from Cambridge, Gloucestershire, UNITED KINGDOM, published 2002 by Springer.
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