At present we may be at the cross-roads in the therapeutic approaches we have for the treatment of the 100 or more rheumatic conditions. This is be- cause we now recognise that although some advances have been made with the development of a large range of non-steroidal and steroidal drugs during the past two decades or so, we now recognise that many, if not all, of these have rather limited effects on many of the disease processes which underlie the manifestations of the various rheumatic states. Advances in molecular bi- ...
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At present we may be at the cross-roads in the therapeutic approaches we have for the treatment of the 100 or more rheumatic conditions. This is be- cause we now recognise that although some advances have been made with the development of a large range of non-steroidal and steroidal drugs during the past two decades or so, we now recognise that many, if not all, of these have rather limited effects on many of the disease processes which underlie the manifestations of the various rheumatic states. Advances in molecular bi- 010gy in the past 5-10 years have enabled these tools to be applied extensive- ly for developing further our understanding of the rheumatic disease processes. In some cases these molecular tools (e. g., ), -interferon, interleukin- 2, T-cell antibodies) have been directly employed as therapies themselves. While the outcome from trials with such agents in rheumatoid arthritis in particular has not been as would have been hoped, these results as with cy- closporin A and low-dose methotrexate in the therapy of rheumatoid arth- ritis have given us important indications for the approach employing what are generally described as "immunomodulators" to control this disease. But this may not be the same type of approach which is desirable for all types of rheumatic conditions. Indeed, even the way which the present range of drugs and other therapies are applied may not be the most effective and safe means of treating different types of arthritic conditions.
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Add this copy of New Developments in Anti-Rheumatic Drugs to cart. $42.69, like new condition, Sold by Fireside Bookshop rated 5.0 out of 5 stars, ships from Stroud, GLOUCESTERSHIRE, UNITED KINGDOM, published 1989 by Kluwer Academic Publishers.
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Like New in No d/j as Published jacket. Size: 8vo-over 7¾"-9¾" tall; Type: Book Considers osteoarthritis, concepts of mode of action and toxicity of anti-inflammatory drugs, animal models of arthritic disease, novel eicosanoid inhibitors, oxyradicals, inflammation and drugs acting on oxyradical production, platelet activating factor antagonists, T cell as a therapeutic target, superoxide dismutase modifications.328pp.
Add this copy of New Developments in Antirheumatic Therapy (Inflammation to cart. $96.63, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 1989 by Springer.
