Natural killer (NK) cells have been the subject of intense investigation. Only in recent years, however, could the molecular mechanisms by which they lyse tumor or virus-infected cells but spare normal cells be elucidated. NK cells express different specialized receptors (NK-R) specific for major histocompatibility complex (MHC) class I molecules. These MHC molecules exert an inhibitory effect on NK cells, i.e. lack of expression of one or more MHC class I alleles - a common event in tumor or virus-infected cells - leads to ...
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Natural killer (NK) cells have been the subject of intense investigation. Only in recent years, however, could the molecular mechanisms by which they lyse tumor or virus-infected cells but spare normal cells be elucidated. NK cells express different specialized receptors (NK-R) specific for major histocompatibility complex (MHC) class I molecules. These MHC molecules exert an inhibitory effect on NK cells, i.e. lack of expression of one or more MHC class I alleles - a common event in tumor or virus-infected cells - leads to NK-mediated target cell lysis. Recently, NK-type receptors have also been identified in a subset of T lymphocytes. MHC/NK-R interaction causes inhibition of T cell activation and functions, an observation which suggests a role for these receptors in the negative control of T cell responses. This volume offers a complete and updated review of the signal transduction and functions of NK cells, as well as their roles in transplantation, anti-tumor response and infectious diseases. Written by experienced investigators, who have contributed significantly to progress in the field, this collection of reviews will be a valuable resource for basic and clinical immunologists, hematologists, oncologists and virologists.
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Add this copy of Molecular Basis of Nk Cell Recognition and Function to cart. $5.03, Sold by Zubal Books rated 5.0 out of 5 stars, ships from Cleveland, OH, UNITED STATES, published 1996 by S Karger Pub.
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*Price HAS BEEN REDUCED by 10% until Monday, June 3 (sale item)* 184 pp., Hardcover, ex library, else text clean and binding tight. -If you are reading this, this item is actually (physically) in our stock and ready for shipment once ordered. We are not bookjackers. Buyer is responsible for any additional duties, taxes, or fees required by recipient's country.
Add this copy of Molecular Basis of Nk Cell Recognition and Function: 64 to cart. $19.97, very good condition, Sold by Bump in the Night Books rated 4.0 out of 5 stars, ships from Kutztown, PA, UNITED STATES, published 1996 by S Karger AG.
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Very Good. pp. 184. Although an ex-library it would be described as New if not for card pouch and spine label. No Markings, No Highlighting, No Underlining.
Add this copy of Molecular Basis of Nk Cell Recognition and Function to cart. $49.93, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 1996 by S Karger Ag.
