This book, Islet Cell Growth Factors, provides a timely contribution to the current thinking regarding the concepts in the area of islet cell regeneration with special reference to insulin secreting beta cells. The contributions are from leaders in the field with a long-standing interest in the area of islet biology. In the first chapter Drs. Dirice and Kulkarni provide a broad introduction to the topic of islet cell regeneration with a focus on growth factor pathways, especially the insulin and insulin-like growth factor ...
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This book, Islet Cell Growth Factors, provides a timely contribution to the current thinking regarding the concepts in the area of islet cell regeneration with special reference to insulin secreting beta cells. The contributions are from leaders in the field with a long-standing interest in the area of islet biology. In the first chapter Drs. Dirice and Kulkarni provide a broad introduction to the topic of islet cell regeneration with a focus on growth factor pathways, especially the insulin and insulin-like growth factor signaling mechanisms affecting beta cells in Type 1, Type 2 and gestational diabetes. This is followed by a contribution by Drs. Granot and Dor who describe an elegant lineage-trace model to confirm that proliferation is one of the major mechanisms underlying beta-cell regeneration in adult rodents. These findings are backed up by Drs. Georgia and Bhushan on cell cycle control in beta cells. Subsequent chapters are focused on proteins downstream of the growth factor pathways in the regulation of beta-cell biology. Thus, Drs. Ham and Stoffers discuss the role of the homeodomain protein, Pdx-1, on beta-cell growth while Dr. Bernal-Mizrachi describes the significance of Akt in beta-cell growth and function. Finally, Drs. Kitamura, Kitamura and Accili highlight the importance of the forkhead protein, FoxO1, in pancreatic betacells. In addition to insulin and IGF-I, several other growth factors play an important role in modulating beta-cell growth. The pathway utilized by the hepatocyte growth factor is discussed by Drs. Gonzalez-Perusa, Alonso and Garcia-Ocana. The significance of pathways relevant for beta-cell proliferation and apoptosis during pregnancy and the postnatal period is nicely presented by Drs. Fujinaka, Wang, Matsushita and Vasavada. Together these chapters provide a comprehensive and mechanistic view of the signaling pathways that are relevant for mammalian beta-cell proliferation. This is an excellent book for the research scientist
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Add this copy of Islet Cell Growth Factors to cart. $63.30, new condition, Sold by GreatBookPrices rated 4.0 out of 5 stars, ships from Columbia, MD, UNITED STATES, published 2019 by CRC Press.
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New. Intended for professional and scholarly audience. In Stock. 100% Money Back Guarantee. Brand New, Perfect Condition, allow 4-14 business days for standard shipping. To Alaska, Hawaii, U.S. protectorate, P.O. box, and APO/FPO addresses allow 4-28 business days for Standard shipping. No expedited shipping. All orders placed with expedited shipping will be cancelled. Over 3, 000, 000 happy customers.
Add this copy of Islet Cell Growth Factors to cart. $63.31, new condition, Sold by Booksplease rated 4.0 out of 5 stars, ships from Southport, MERSEYSIDE, UNITED KINGDOM, published 2019 by CRC Press.
Add this copy of Islet Cell Growth Factors to cart. $72.32, like new condition, Sold by GreatBookPrices rated 4.0 out of 5 stars, ships from Columbia, MD, UNITED STATES, published 2019 by CRC Press.
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Seller's Description:
Fine. Intended for professional and scholarly audience. In Stock. 100% Money Back Guarantee. Brand New, Perfect Condition, allow 4-14 business days for standard shipping. To Alaska, Hawaii, U.S. protectorate, P.O. box, and APO/FPO addresses allow 4-28 business days for Standard shipping. No expedited shipping. All orders placed with expedited shipping will be cancelled. Over 3, 000, 000 happy customers.
Add this copy of Islet Cell Growth Factors to cart. $72.33, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 2019 by CRC Press.
