It is now over 30 years since the idea of ion-conducting pores burst on the elec- trophysiological scene, 15 years since these were generalIy realized to be mem- brane-spanning proteins, and 10 years since the first observations of single ion channels from higher organisms were made. During the past 5 years, several integral membrane channel proteins have been purified in a functionalIy competent state: the nicotinic acetylcholine receptor, the Na + channel, mitochondrial "VDAC," and a variety of porins. The stage is thus ...
Read More
It is now over 30 years since the idea of ion-conducting pores burst on the elec- trophysiological scene, 15 years since these were generalIy realized to be mem- brane-spanning proteins, and 10 years since the first observations of single ion channels from higher organisms were made. During the past 5 years, several integral membrane channel proteins have been purified in a functionalIy competent state: the nicotinic acetylcholine receptor, the Na + channel, mitochondrial "VDAC," and a variety of porins. The stage is thus set to attack ion channels in the same ways that biochemists have been attacking enzymes for decades: isolation folIowed by functional analysis in as simple a system as possible, with a view towards understanding the molecular mechanisms ofthe protein's behavior and how this is related to the underlying molecular structure. This is always a daunting task, alI the more so with ion channels because of our still primitive and scanty understanding of channel structures and because of the difficulty in iso- lating functionally active channel proteins. In this volume, which can be considered a biochemically slanted companion to Sakmann and Neher's Single-Channel Recording, I have tried to present a view of the current landscape of ion-channel reconstitution. These chapters illustrate not only the different approaches and techniques of the major practitioners of ion- channel reconstitution but, as importantly, the varied motivations for doing this kind of work.
Read Less
Add this copy of Ion Channel Reconstitution to cart. $26.27, good condition, Sold by HPB-Red rated 5.0 out of 5 stars, ships from Dallas, TX, UNITED STATES, published 1986 by Springer.
Choose your shipping method in Checkout. Costs may vary based on destination.
Seller's Description:
Good. Connecting readers with great books since 1972! Used textbooks may not include companion materials such as access codes, etc. May have some wear or writing/highlighting. We ship orders daily and Customer Service is our top priority!
Add this copy of Ion Channel Reconstitution to cart. $29.28, good condition, Sold by ThriftBooks-Atlanta rated 5.0 out of 5 stars, ships from Austell, GA, UNITED STATES, published 1986 by Springer.
Add this copy of Ion Channel Reconstitution to cart. $49.95, very good condition, Sold by Story Shop rated 4.0 out of 5 stars, ships from Elwood, IN, UNITED STATES, published 1986 by Plenum Press.
Choose your shipping method in Checkout. Costs may vary based on destination.
Seller's Description:
Very Good with no dustjacket. 0306421364. Nice and clean. Light cover wear. Name stamped on the page edges (small and light). No internal marks or writing. Spine is faded.; Large 8vo 9"-10"; 577 pages.
Add this copy of Ion Channel Reconstitution to cart. $78.80, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 1986 by Kluwer Academic/Plenum Publish.
Add this copy of Ion Channel Reconstitution to cart. $103.32, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2013 by Springer.
Add this copy of Ion Channel Reconstitution to cart. $135.33, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 2013 by Springer.
Add this copy of Ion Channel Reconstitution to cart. $181.99, new condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 2013 by Springer.