Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field's history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter ...
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Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field's history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.
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Add this copy of Innovations for Next-Generation Antibody-Drug to cart. $60.91, very good condition, Sold by Devils In The Detail Ltd rated 5.0 out of 5 stars, ships from Oxford, OXFORDSHIRE, UNITED KINGDOM, published 2018 by Humana.
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Very Good. Picture Shown is For Illustration Purposes Only, Please See Below For Further DetailsCONDITION-VERY GOOD light wear and scuff marks to boards, pages in nice condition, shipped from the UK. Sewn binding. Cloth over boards. 357 p. Contains: Unspecified, Illustrations, black & white, Illustrations, color. Cancer Drug Discovery & Development.
Add this copy of Innovations for Next-Generation Antibody-Drug to cart. $102.11, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 2018 by Humana.
Add this copy of Innovations for Next-Generation Antibody-Drug to cart. $159.69, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2019 by Humana.
Add this copy of Innovations for Next-Generation Antibody-Drug to cart. $159.69, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2018 by Humana.
Choose your shipping method in Checkout. Costs may vary based on destination.
Seller's Description:
New. Sewn binding. Cloth over boards. 357 p. Contains: Unspecified, Illustrations, black & white, Illustrations, color. Cancer Drug Discovery & Development.
