The behavior of lymphocytes in the immune system depends on encounters with antigens. These bind to immunoreceptors on the surface of T-cells and B-cells, activating a variety of signal transduction pathways that control cell survival, proliferation, differentiation, and effector functions. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology includes contributions covering the structures of the T-cell and B-cell immunoreceptors, the numerous kinases and adaptors that ...
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The behavior of lymphocytes in the immune system depends on encounters with antigens. These bind to immunoreceptors on the surface of T-cells and B-cells, activating a variety of signal transduction pathways that control cell survival, proliferation, differentiation, and effector functions. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology includes contributions covering the structures of the T-cell and B-cell immunoreceptors, the numerous kinases and adaptors that associate with their intracellular tails, and the downstream signaling pathways that lead to transcription of interleukins and other outputs. Other contributions examine the roles of other receptors, co-stimulatory signals, and innate immune responses in regulation of immunoreceptor signaling. The spatial organization of the immunological synapses connecting lymphocytes and antigen-presenting cells is also discussed, along with the role of the cytoskeleton in immunoreceptor function. Computational models of the signaling processes complete the volume, making it essential reading for systems biologists as well as all immunologists and cell biologists interested in understanding how lymphocytes function.
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Add this copy of Immunoreceptor Signaling: A Subject Collection from to cart. $103.15, new condition, Sold by Ria Christie Books rated 5.0 out of 5 stars, ships from Uxbridge, MIDDLESEX, UNITED KINGDOM, published 2010 by Cold Spring Harbor Laboratory Press.
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New. Sewn binding. Paper over boards. 282 p. Contains: Illustrations, color, Tables, black & white, Figures. Cold Spring Harbor Perspectives in Biology.
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New. Sewn binding. Paper over boards. 282 p. Contains: Illustrations, color, Tables, black & white, Figures. Cold Spring Harbor Perspectives in Biology.
Add this copy of Immunoreceptor Signaling: A Subject Collection from to cart. $132.26, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2010 by Cold Spring Harbor Laboratory Press.
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New. Sewn binding. Paper over boards. 282 p. Contains: Illustrations, color, Tables, black & white, Figures. Cold Spring Harbor Perspectives in Biology.
Add this copy of Immunoreceptor Signaling to cart. $152.66, new condition, Sold by Revaluation Books rated 4.0 out of 5 stars, ships from Exeter, DEVON, UNITED KINGDOM, published 2010 by Cold Spring Harbor Laboratory Pr.
