The recent successful challenge of locating the gene responsible for male differentiation is described, and a cause of abnormal male sex differentiation, the androgen insensitivity syndrome, is thoroughly reviewed with particular emphasis on the molecular biology of the androgen receptor and its mutations. The susceptibility of the gonad and abnormalities of male differentiation is discussed along with clinical considerations in the management of these children and young adults. As a result of its increased availability, ...
Read More
The recent successful challenge of locating the gene responsible for male differentiation is described, and a cause of abnormal male sex differentiation, the androgen insensitivity syndrome, is thoroughly reviewed with particular emphasis on the molecular biology of the androgen receptor and its mutations. The susceptibility of the gonad and abnormalities of male differentiation is discussed along with clinical considerations in the management of these children and young adults. As a result of its increased availability, growth hormone is now being examined as a therapeutic option for children with a variety of causes of short stature. Chapters in this book outline the many initial benefits seen for most of these children, but they also discuss the concerns that are being raised by this therapy in regard to possible benefits to the final height and growth during puberty. This book reflects the remarkable progress over the last few years in understanding the mechanisms of normal and abnormal gr
Read Less
Add this copy of Multiple Criteria Decision Making and Its Applications to cart. $94.15, new condition, Sold by discount_scientific_books rated 5.0 out of 5 stars, ships from Sterling Heights, MI, UNITED STATES, published 1993 by Routledge.