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Fatty Acid and Lipotoxicity in Obesity and Diabetes

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Fatty Acid and Lipotoxicity in Obesity and Diabetes - Bock, Gregory R. (Editor), and Goode, Jamie A. (Editor)
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The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle. This book deals with the molecular aspects ...

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Fatty Acid and Lipotoxicity in Obesity and Diabetes 2007, John Wiley & Sons Inc, New York

ISBN-13: 9780470057643

Hardcover