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Erythropoietin: From Physiology to conical Trials via molecular biology
I. Molecular and Cellular biolgy
2. The molecular Biology of Erythropoietin
3. The STructure-Function Relationship of Erythropoietin
4. The Regulation of erythropoietin gene expression
5. The biogenesis of erythropoietin in vivo
6. Renal Function and Oxygn Sensing
7. The erythroid Response to Erythropoietin
8. The Physiology and Biochenistry of Erythropoietin receptors
9. The molecular biology of Erythropoietin receptors
10. The pharmacokinetics and ,etabolism of Erythropoietin
11. Erythropoietin in Health and Disease
II. CLINICAL TRIALS
12. Recombinant Human Erythropoietin (Epoetin Alfa) in Patients on hemodialysis: United States
13. Recomginant Human Erythropoietin (Epoetin Alfa) in Patients w/ Renal anemia: Japan
14. Recombinant Human Erythropoietin (Epietin Alfa) in Anemic Patients on hemodialysis: Canada
15. Recombinant Human Erythropoietin (Epoetin Beta) in Patients with End-Stage Renal disease: US and Japan
16. Recombinant human Erythropoietin (Epoetin Alfa and Beta) in Patients on Hemodialysis: Western Europe
17. Recombinant human Erythropoietin (Epoetin Alfa) in Patients with Predialysis Renal Failure
18. Recombinant human Erythropoietin (Epoetin Alfa and Beta) in Patients on Ambulatory Peritoneal Dialysis
19. REcombinant human Erythropoietin (Epoetin Beta) in children with Renal Anemia: Western Europe
20. Recombinant Human Erythropoietin (Epoetin Alfa) in Patients w/ the anemia of Prematurity
21. Recombinant human Erythropoietin (Epoitin Alfa) in Autologous Blood donors and Perisurgican Patients.
22> Recombinant Human Erythropoietin (epoetin Alfa) in Patients with the Anemia of chronic disease
23. Recombinant human Erythropoietin (Epoitin Alfa) i Patients with AIS and AZT-induced Anemia
24. Summary and Conclusions