Coronary pressure measurement has emerged over the last few years as a major step forward in the invasive assessment of coronary artery disease. This was due on the one hand to major technical progress in developing pressure-monitoring guide wires, and on the other to a theoretical innovation, the concept of coronary pressure-derived fractional flow reserve, which closely relates distal coronary pressure to myocardial blood flow during maximum arteriolar vasodilation. In the catheterization laboratory, this new approach ...
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Coronary pressure measurement has emerged over the last few years as a major step forward in the invasive assessment of coronary artery disease. This was due on the one hand to major technical progress in developing pressure-monitoring guide wires, and on the other to a theoretical innovation, the concept of coronary pressure-derived fractional flow reserve, which closely relates distal coronary pressure to myocardial blood flow during maximum arteriolar vasodilation. In the catheterization laboratory, this new approach enables an on-the-spot diagnosis as to what extent a given epicardial stenosis contributes to reversible myocardial ischemia and the decision as to whether revascularization of the stenosis is warranted or not. In addition, pressure-derived fractional flow reserve appears to be a useful index in monitoring and guiding coronary intervention, including stent deployment.
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