Featuring contributions from researchers in the diverse fields of neuroinjury, myocardial injury, diabetes, shock, and inflammation, this text examines the current status of the field of poly (ADP-ribose) polymerase (PARP) and cell death. Cell Death: The Role of PARP also explores PARP and apoptosis, PARP and DNA repair, as well as PARP and regulation of gene expression. Separate chapters focus on developments in the areas of pharmacological inhibition of PARP and on novel ways of measuring PARP activation. Furthermore, the ...
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Featuring contributions from researchers in the diverse fields of neuroinjury, myocardial injury, diabetes, shock, and inflammation, this text examines the current status of the field of poly (ADP-ribose) polymerase (PARP) and cell death. Cell Death: The Role of PARP also explores PARP and apoptosis, PARP and DNA repair, as well as PARP and regulation of gene expression. Separate chapters focus on developments in the areas of pharmacological inhibition of PARP and on novel ways of measuring PARP activation. Furthermore, the emerging field of PARP isoforms is addressed. This book not only presents a state-of-the-art overview of the field, but serves as a catalyst for further research in this area.
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