The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. The traditional process of drug development is long and expensive, but simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of bench top bioassay techniques useful for natural product and pharmaceutical chemists involved in drug discovery and pharmacognosy. The majority of these bioassays are presented in a step-by-step format, ...
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The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. The traditional process of drug development is long and expensive, but simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of bench top bioassay techniques useful for natural product and pharmaceutical chemists involved in drug discovery and pharmacognosy. The majority of these bioassays are presented in a step-by-step format, so they could even be implemented by technical personnel with little background in microbiology, biochemistry, or pharmacology.
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