The present study was designed to investigate the antiglycation potential of hydro-alcoholic and alkaloidal fractions of selected plants. Seeds of Trigonella foenum-graecum, bulbs of Allium sativum, fruits of Momordica charantia. and leaves of Gymnema sylvestre were selected. The protein glycation inhibitory activity of these plants was evaluated using glucose-bovine serum albumin assay. Among the hydroalcoholic extracts, Trigonella-foenum graecum showed highest antiglycation activity (IC50 = 53.53 ??? 1.24 ???g/ml) ...
Read More
The present study was designed to investigate the antiglycation potential of hydro-alcoholic and alkaloidal fractions of selected plants. Seeds of Trigonella foenum-graecum, bulbs of Allium sativum, fruits of Momordica charantia. and leaves of Gymnema sylvestre were selected. The protein glycation inhibitory activity of these plants was evaluated using glucose-bovine serum albumin assay. Among the hydroalcoholic extracts, Trigonella-foenum graecum showed highest antiglycation activity (IC50 = 53.53 ??? 1.24 ???g/ml) followed by Allium sativum (IC50 = 68.36 ??? 1.56 ???g/ml), Momordica charantia (IC50 = 85.16 ??? 1.87 ???g/ml) and Gymnema sylvestre (IC50 = 103.66 ??? 2.09 ???g/ml). Among the alkaloidal fractions, the highest antiglycation activity was shown by Trigonella-foenum graecum (IC50 = 31.56 ??? 1.36 ???g/ml) followed by Allium sativum (IC50 = 40.46 ??? 1.59 ???g/ml), Momordica charantia (IC50 = 54.8 ??? 2.12 ???g/ml) and Gymnema sylvestre (IC50 = 64.50 ??? 1.73 ???g/ml). Aminoguanidine, a standard drug, showed 100% inhibition (IC50 = 22.45 ??? 1.89 ???g/ml). Alkaloidal extracts of these plants possess antiglycation activity and may be explored in diabetic complications
Read Less
Add this copy of Advanced glycation inhibitory potential of certain to cart. $37.01, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2014 by LAP Lambert Academic Publishing.
Add this copy of Advanced Glycation Inhibitory Potential of Certain to cart. $71.13, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Newport Coast, CA, UNITED STATES, published 2014 by LAP LAMBERT Academic Publishin.
