This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1914 Excerpt: ...of the fluid obtained by the steam distillation of rotten fish to which is added a little Lemco broth and milk, and Bannerman believes that he is correct.1 Williams has grown a non-acid-fast streptothrix in ordinary broth, and has also cultivated acid-fast bacilli in a modified Rost medium (substituting distilled water ...
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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1914 Excerpt: ...of the fluid obtained by the steam distillation of rotten fish to which is added a little Lemco broth and milk, and Bannerman believes that he is correct.1 Williams has grown a non-acid-fast streptothrix in ordinary broth, and has also cultivated acid-fast bacilli in a modified Rost medium (substituting distilled water for the fish distillate). The writer has also grown a non-acid-fast streptothrix from a case of leprosy on brain agar containing the juice from disintegrated B. megaterium. As a result of these alleged positive cultural results, it has been surmised that the B. leprc e is really a streptothrix, that it is acid-fast only under certain conditions, viz. in the body or in media containing fat, and that under cultivation the streptothrix may break up into non-acid-fast diphtheroid bacilli or into acid-fast leproid bacilli. On the other hand, Fraser and Fletcher2 have made 373 inoculations from 33 non-ulcerating cases of leprosy on a variety of culture media with entirely negative results. More work is therefore required before it can be definitely stated that the leprosy bacillus has been cultivated. 1 Brit. Med. Journ., 1908, vol. i. p. 802. 2 Proc. Roy. Soc. Land., B 1911. A certain number of positive results of the inoculation of leprous material into the lower animals have been reported by Ortmann and others. Nicolle3 has reported the successful inoculation of a macaque monkey, but most of the attempts have ended in failure; positive results are open to criticism and may be fallacious, for lepers not infrequently suffer from coincident tuberculosis, and the animals therefore may have been infected with tuberculosis. Japanese dancing mice are also stated to be slightly susceptible. The local lesion induced in animals may be simply inflam...
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