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ODE/PDE a-synuclein Models for Parkinson's Disease

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ODE/PDE a-synuclein Models for Parkinson's Disease - Schiesser, William E.
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ODE/PDE Alpha-Synuclein Models for Parkinson's Disease discusses a mechanism for the evolution of Parkinson's Disease (PD) based on the dynamics of the protein a-synuclein, a monomer that has been implicated in this disease. Specifically, a-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the a-synuclein monomer and polymer, and then ...

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